Complication: Kidney Failure

Kidney Failure is a complication that may be a result of impaired kidney function due to multiple myeloma. Kidney Failure, also referred to as renal failure, is caused by the kidneys not being able to filter the proteins secreted by malignant plasma cells. Hypercalcemia, or elevate protein levels in the blood, also contribute to kidney failure complications in myeloma patients.

More than half of patients with myeloma experience kidney problems at some point in the course of their disease. Kidney impairment can also be caused by other conditions, such as hypertension and diabetes, and some medications can affect the kidney as well. Blood tests can detect certain proteins (such as creatinine) that are indicative of reduced kidney function. A decrease in the amount of urine is one sign of kidney problems, and patients should let their doctors know if they experience any changes in their urination.