MULTIPLE MYELOMA KNOWLEDGE CENTER

How is Pomalyst administered?

Pomalyst® (pomalidomide, Celgene) is an oral medication that is taken along with dexamethasone. The recommended starting dose of Pomalyst is 4 mg once daily for three out of four weeks (days 1-21 of each 28-day cycle). Each Pomalyst capsule should be taken with water. Pomalyst should not be taken with food and should be taken at least 2 hours before or 2 hours after a meal. Dexamethasone is taken at a dose of 40 mg weekly, which is also referred to as “low-dose dexamethasone.” The dose of dexamethasone is reduced to 20 mg weekly for patients older than 75 years of age.

Typically, aspirin or another blood thinner is taken along with Pomalyst and low-dose dexamethasone.

Pomalyst and low-dose dexamethasone are taken for as long as they continue to work against the myeloma.