Farydak Administration - Farydak Dosing - Panobinostat Dosing

MULTIPLE MYELOMA KNOWLEDGE CENTER

How is Farydak Administered?

Farydak® (panobinostat, Novartis) is an oral medication. Farydak capsules should be taken once on each scheduled day at about the same time, along with a full glass of water. Farydak can be taken with or without food.

Farydak is taken along with Velcade® (bortezomib, Takeda Oncology; given as a subcutaneous injection or intravenous infusion) and oral dexamethasone. The recommended starting dose of Farydak is 20 mg, taken once every other day for 3 doses per week, in Weeks 1 and 2 of each 21-day cycle. Patients are typically treated up to 8 cycles. Patients who are clinically benefitting from treatment and are not experiencing severe side effects can receive continued treatment for an additional 8 cycles.

While taking Farydak, patients should avoid star fruit, pomegranate or pomegranate juice, and grapefruit or grapefruit juice because these foods can affect the amount of Farydak in the blood.