MULTIPLE MYELOMA KNOWLEDGE CENTER

How is Selinexor currently being studied in myeloma?

Selinexor is being evaluated in several clinical trials in relapsed and/or refractory myeloma, including:

  • In combination with dexamethasone in a Phase 2b study (STORM) in patients whose myeloma is refractory to Velcade® (bortezomib, Takeda Oncology), Revlimid® (lenalidomide, Celgene), Kyprolis® (carfilzomib, Onyx Therapeutics), and Pomalyst® (pomalidomide, Celgene)

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  • In combination with the backbone treatments Pomalyst-dex, Velcade-dex or Revlimid-dex in a Phase 1b/2 study (STOMP)

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  • In combination with Doxil® (doxorubicin HCl liposome injection, Janssen) in a Phase1/2 study

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  • In combination with Kyprolis and dexamethasone in a Phase 1 study

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