Multiple Myeloma Symptoms


The symptoms of multiple myeloma may vary by patient, with the early stages of myeloma often presenting no visible symptoms or signs. The symptoms of myeloma may be vague or similar to those of the other conditions. Certain myeloma symptoms may also be the result of complications of the disease. Remember that not all individuals with myeloma will have symptoms and that it is unusual for any one individual to have all of these symptoms. In addition, advances in treatment allow for symptoms to be prevented and managed.

The most common multiple myeloma symptoms may include:

• Bone pain or bone fractures
• Fatigue
• Increased vulnerability to infections
• Increased or decreased urination
• Restlessness – eventually followed by extreme weakness and fatigue
• Confusion
• Increased thirst
• Nausea and vomiting
• Loss of appetite and weight loss
• Impaired kidney function

Bone lesions – Bone pain or fractures are caused by tiny fractures in the bone (lytic bone lesions) made by the accumulation of plasma cells; weakened bone structure.

Low blood count — Low levels of red blood cells in the blood cause anemia related fatigue. Low blood count may also include low levels of white blood cells which increase susceptibility to infections and weaken the immune system.

Hypercalcemia — Changes in urination, restlessness, confusion, increased thirst, nausea and loss of appetite are usually a result of high levels of calcium in the blood.

Impaired kidney function – Impaired Kidney Function can result in a number of additional complications and is an effect of the kidneys being overworked by the excess protein and calcium in the blood.