|Management of Common Side Effects of Thalomid|
|If You Have||Your Doctor May|
|Drowsiness||Adjust the schedule or dose. Have you take Thalomid between 7:00 p.m. and 10:00 p.m. Reduce the dose or stop the drug temporarily (if drowsiness is severe).|
|Peripheral neuropathy||Reduce dose when the symptoms begin; if symptoms don’t progress, maintain reduced dose. Stop the drug temporarily (if neuropathy is severe) and restart treatment at a lower dose if symptoms improve.|
|Dizziness||Tell you to avoid sudden change in position from lying or sitting to standing. Adjust the dose if dizziness is severe.|
|Slow pulse||Reduce the dose or stop the drug if heart rate becomes very low or is associated with tiredness or dizziness.|
|Constipation||Tell you to increase fluid intake.
Tell you to increase fiber intake.
Recommend that you use a stool softener daily.
Suggest that you take a laxative as needed.
|Dry skin/rash||Tell you to use lotion for dry skin.
Stop therapy (if a rash develops).
Recommend that you use antihistamines or topical steroids to control itching.
Evaluate the condition to rule out serious skin reactions, restart treatment with Thalomid at a lower dose, and monitor you closely for skin reactions.